Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A182FBI2Uncharacterized protein. (1768 aa)    
Predicted Functional Partners:
A0A1Y9G9P8
Uncharacterized protein.
   
 0.956
A0A2C9GGZ8
Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.
   
 0.951
A0A182FW87
Uncharacterized protein.
    
 0.944
A0A182FVA0
Mitogen-activated protein kinase.
    
 0.931
A0A182FCA5
Uncharacterized protein.
   
 0.900
A0A182FNT4
Uncharacterized protein.
   
 0.873
A0A182F3Z2
Uncharacterized protein.
    
 0.871
A0A182F118
Uncharacterized protein.
   
 0.867
A0A182FCD8
Sm domain-containing protein.
    
 0.865
A0A182F9W9
Uncharacterized protein.
    
 0.857
Your Current Organism:
Anopheles albimanus
NCBI taxonomy Id: 7167
Other names: A. albimanus
Server load: low (16%) [HD]