Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
A0A182FC01Lipase domain-containing protein. (348 aa)    
Predicted Functional Partners:
A0A182F252
Aspartate aminotransferase.
   
 0.989
A0A182FVT2
Citrate synthase; Belongs to the citrate synthase family.
  
 0.984
A0A182FH95
ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
 0.972
A0A182F685
Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.
  
 0.968
A0A1Y9G8K1
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
  
 0.941
A0A182FQY2
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.927
A0A182FM08
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 0.909
A0A182FTY5
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
 0.909
A0A182FTY6
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
 0.909
A0A182FBF0
Dihydrolipoyl dehydrogenase.
  
 0.904
Your Current Organism:
Anopheles albimanus
NCBI taxonomy Id: 7167
Other names: A. albimanus
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