Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A182FC29Uncharacterized protein. (489 aa)    
Predicted Functional Partners:
A0A182FAU7
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
   
 0.938
A0A182F8T6
SAS-6_N domain-containing protein.
   
 0.885
A0A182FMV3
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.878
A0A182F495
Uncharacterized protein.
   
 0.860
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 0.824
A0A182FLY5
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
    
 0.820
A0A182FAF4
DNA helicase; Belongs to the MCM family.
   
 0.819
A0A182FLX6
Uncharacterized protein.
    
 0.815
A0A182F6R7
Uncharacterized protein.
    
 0.802
A0A182F611
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
    
 0.800
Your Current Organism:
Anopheles albimanus
NCBI taxonomy Id: 7167
Other names: A. albimanus
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