STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A182FCA5Uncharacterized protein. (409 aa)    
Predicted Functional Partners:
A0A182FHB6
Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.
   
 0.999
A0A182F944
VPS37 C-terminal domain-containing protein.
    
 0.998
A0A2C9GGZ8
Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.
    
 0.989
A0A182FM54
Uncharacterized protein.
    
 0.974
A0A182FQQ9
Uncharacterized protein.
    
 0.974
A0A1Y9G8A6
60S ribosomal protein L40.
    
 0.973
A0A182FHF9
Uncharacterized protein.
   
 0.956
A0A1Y9G9P8
Uncharacterized protein.
   
 0.951
A0A182FNT4
Uncharacterized protein.
   
 0.948
A0A182F8C7
Ubiquitin-like domain-containing protein.
    
 0.943
Your Current Organism:
Anopheles albimanus
NCBI taxonomy Id: 7167
Other names: A. albimanus
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