Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A182FDF8Uncharacterized protein; Belongs to the HAD-like hydrolase superfamily. (320 aa)    
Predicted Functional Partners:
A0A182FC86
Uncharacterized protein.
     
 0.906
A0A182FF11
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.906
A0A182FF12
Uncharacterized protein.
     
 0.906
A0A182FLY3
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.906
A0A182FGY7
Uncharacterized protein.
  
  
 
0.905
A0A182FTS5
STAS domain-containing protein.
  
  
 0.657
A0A182FW38
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
     
  0.635
A0A182FM94
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
     
 0.620
A0A182FH92
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
    
  0.569
A0A182FHD4
Uncharacterized protein.
    
  0.569
Your Current Organism:
Anopheles albimanus
NCBI taxonomy Id: 7167
Other names: A. albimanus
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