Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A182FDP3Thioredoxin peroxidase 5. (228 aa)    
Predicted Functional Partners:
A0A182FK07
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
   
 0.945
A0A182FM24
Glutathione S-transferase sigma class 1; Belongs to the GST superfamily.
   
 0.919
A0A182F1D3
Uncharacterized protein.
  
 
 0.903
A0A182FJI4
Uncharacterized protein.
  
 
 0.903
A0A182FK64
Glutathione synthetase.
   
 
 0.903
A0A182FMX1
Uncharacterized protein.
  
 
 0.903
A0A182FUL4
Thioredoxin peroxidase 4.
  
  
 
0.903
A0A182FP75
Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
     
  0.900
A0A2C9GH06
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.876
A0A182FZL3
Glutathione S-transferase omega class 1; Belongs to the GST superfamily.
   
 0.845
Your Current Organism:
Anopheles albimanus
NCBI taxonomy Id: 7167
Other names: A. albimanus
Server load: low (14%) [HD]