Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
A0A182FG02Transket_pyr domain-containing protein. (420 aa)    
Predicted Functional Partners:
A0A182FIU4
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.999
A0A182FL64
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
 0.999
A0A182FBF0
Dihydrolipoyl dehydrogenase.
  
 0.998
A0A182FM70
Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 0.996
A0A182F7F1
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.987
A0A182FLV1
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.971
A0A182FDZ7
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
   
 0.948
A0A182F1I7
Lipoyl-binding domain-containing protein.
 
 0.947
A0A1I8JSV1
Uncharacterized protein.
  
 
 0.938
A0A182FA10
Lipoyl-binding domain-containing protein.
  
 0.933
Your Current Organism:
Anopheles albimanus
NCBI taxonomy Id: 7167
Other names: A. albimanus
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