STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A182FHK83-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (470 aa)    
Predicted Functional Partners:
A0A182FPY6
3-hydroxy-3-methylglutaryl coenzyme A reductase.
  
 
 0.998
A0A182FTX4
Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.997
A0A182FFL4
Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.996
A0A182FSQ2
Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.996
A0A182FV00
Cathepsin L; Belongs to the peptidase C1 family.
  
 0.996
A0A182FHR6
Uncharacterized protein.
    
 0.946
A0A182FBY1
Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.935
A0A1Y9G8K1
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
     
 0.928
A0A182FMZ3
ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
   
 
 0.924
A0A182F7H7
Nudix hydrolase domain-containing protein.
  
  
 0.916
Your Current Organism:
Anopheles albimanus
NCBI taxonomy Id: 7167
Other names: A. albimanus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.