STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A182N2L9Histone domain-containing protein; Belongs to the histone H2B family. (79 aa)    
Predicted Functional Partners:
A0A182N1S6
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
  
 0.999
A0A182NCC9
Histone H2A; Belongs to the histone H2A family.
   
 0.994
A0A182NB27
TPR_REGION domain-containing protein.
    
 0.991
A0A182N2L8
Histone H2A; Belongs to the histone H2A family.
  
 0.982
A0A182ND65
Histone H2A; Belongs to the histone H2A family.
  
 0.982
A0A182N3Y0
Histone H2A; Belongs to the histone H2A family.
  
 0.981
A0A182ND72
Uncharacterized protein; Belongs to the histone H2A family.
  
 0.981
A0A182N5V4
TPR_REGION domain-containing protein.
   
 0.976
A0A182N1S5
Histone H3; Belongs to the histone H3 family.
   
 0.975
A0A182N504
Histone H3; Belongs to the histone H3 family.
   
 0.975
Your Current Organism:
Anopheles dirus
NCBI taxonomy Id: 7168
Other names: A. dirus, Anopheles (Cellia) dirus, Anopheles dirus sensu stricto
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.