STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A182NDM9Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (967 aa)    
Predicted Functional Partners:
A0A182N2A8
GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.
  
  
 0.947
A0A182NBE3
ATP-dependent Clp protease proteolytic subunit.
  
 
 0.885
A0A182N661
Uncharacterized protein.
  
 
 0.864
A0A182N7D8
TPR_REGION domain-containing protein.
   
 0.835
A0A182N0B5
PDZ domain-containing protein.
    
 0.801
A0A182N997
AAA domain-containing protein.
  
 
 0.796
A0A182N6E7
Uncharacterized protein; Belongs to the chaperonin (HSP60) family.
  
 0.789
A0A182NP38
AAA domain-containing protein.
  
 
 0.785
A0A182NVI8
AAA domain-containing protein.
  
 
0.780
A0A182NAE0
Uncharacterized protein.
    
 0.764
Your Current Organism:
Anopheles dirus
NCBI taxonomy Id: 7168
Other names: A. dirus, Anopheles (Cellia) dirus, Anopheles dirus sensu stricto
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