STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A182NIG5Uncharacterized protein. (221 aa)    
Predicted Functional Partners:
A0A182NJ64
Uncharacterized protein.
    
 0.854
A0A182N1S6
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.804
A0A182NL94
DNA helicase; Belongs to the RuvB family.
    
 0.803
A0A182NGE8
Uncharacterized protein; Belongs to the actin family.
    
 0.799
A0A182NP53
RPOLD domain-containing protein.
   
 0.798
A0A182N850
Uncharacterized protein.
   
 0.795
A0A182N2L9
Histone domain-containing protein; Belongs to the histone H2B family.
    
 0.747
A0A182N5A0
WD_REPEATS_REGION domain-containing protein.
    
 0.744
A0A182NU04
YL1_C domain-containing protein.
    
 0.743
A0A182N8Q9
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.742
Your Current Organism:
Anopheles dirus
NCBI taxonomy Id: 7168
Other names: A. dirus, Anopheles (Cellia) dirus, Anopheles dirus sensu stricto
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.