STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A182NVG2Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (714 aa)    
Predicted Functional Partners:
A0A182N8F9
Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
  
0.975
A0A182NN15
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.900
A0A182NTZ0
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
    
 0.879
A0A182NUW0
Nudix hydrolase domain-containing protein.
     
 0.852
A0A182NJZ0
Elp3 domain-containing protein.
   
 
 0.848
A0A182NJ51
GTP_cyclohydroI domain-containing protein.
     
 0.847
A0A182N4S4
Phosphodiesterase.
   
 0.811
A0A182N3K6
Probable cGMP 3',5'-cyclic phosphodiesterase subunit delta.
    
 0.781
A0A182NGQ3
Phosphodiesterase.
   
 0.738
A0A182NGQ5
GAF domain-containing protein.
   
 0.738
Your Current Organism:
Anopheles dirus
NCBI taxonomy Id: 7168
Other names: A. dirus, Anopheles (Cellia) dirus, Anopheles dirus sensu stricto
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