A0A4Y7SC37 protein (Coprinellus micaceus) - STRING interaction network

Nodes:

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

A0A4Y7SC37

Uncharacterized protein. (164 aa)

Predicted Functional Partners:

A0A4Y7TWK0

0.955

A0A4Y7SMY0

0.945

A0A4Y7U0G9

0.942

A0A4Y7SR72

0.898

A0A4Y7TFI1

0.898

A0A4Y7T963

0.857

A0A4Y7TIP8

0.854

A0A4Y7STJ5

0.853

A0A4Y7TE47

0.853

A0A4Y7SVN3

0.662

Your Current Organism:

Coprinellus micaceus

NCBI taxonomy Id: 71717
Other names: C. micaceus, Coprinus micaceus

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A4Y7SC37	A0A4Y7SMY0	Uncharacterized protein.	P-loop containing nucleoside triphosphate hydrolase protein.	0.945
A0A4Y7SC37	A0A4Y7SR72	Uncharacterized protein.	P-loop containing nucleoside triphosphate hydrolase protein.	0.898
A0A4Y7SC37	A0A4Y7STJ5	Uncharacterized protein.	Nuclear condensin complex protein.	0.853
A0A4Y7SC37	A0A4Y7SVN3	Uncharacterized protein.	Uncharacterized protein.	0.662
A0A4Y7SC37	A0A4Y7T963	Uncharacterized protein.	RecF/RecN/SMC protein.	0.857
A0A4Y7SC37	A0A4Y7TE47	Uncharacterized protein.	SMC hinge domain-containing protein.	0.853
A0A4Y7SC37	A0A4Y7TFI1	Uncharacterized protein.	Chromosome structural maintenance protein smc5.	0.898
A0A4Y7SC37	A0A4Y7TIP8	Uncharacterized protein.	Structural maintenance of chromosomes protein.	0.854
A0A4Y7SC37	A0A4Y7TWK0	Uncharacterized protein.	Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.	0.955
A0A4Y7SC37	A0A4Y7U0G9	Uncharacterized protein.	SP-RING-type domain-containing protein.	0.942
A0A4Y7SMY0	A0A4Y7SC37	P-loop containing nucleoside triphosphate hydrolase protein.	Uncharacterized protein.	0.945
A0A4Y7SMY0	A0A4Y7SR72	P-loop containing nucleoside triphosphate hydrolase protein.	P-loop containing nucleoside triphosphate hydrolase protein.	0.987
A0A4Y7SMY0	A0A4Y7STJ5	P-loop containing nucleoside triphosphate hydrolase protein.	Nuclear condensin complex protein.	0.726
A0A4Y7SMY0	A0A4Y7SVN3	P-loop containing nucleoside triphosphate hydrolase protein.	Uncharacterized protein.	0.793
A0A4Y7SMY0	A0A4Y7T963	P-loop containing nucleoside triphosphate hydrolase protein.	RecF/RecN/SMC protein.	0.947
A0A4Y7SMY0	A0A4Y7TE47	P-loop containing nucleoside triphosphate hydrolase protein.	SMC hinge domain-containing protein.	0.718
A0A4Y7SMY0	A0A4Y7TFI1	P-loop containing nucleoside triphosphate hydrolase protein.	Chromosome structural maintenance protein smc5.	0.987
A0A4Y7SMY0	A0A4Y7TIP8	P-loop containing nucleoside triphosphate hydrolase protein.	Structural maintenance of chromosomes protein.	0.902
A0A4Y7SMY0	A0A4Y7TWK0	P-loop containing nucleoside triphosphate hydrolase protein.	Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.	0.998
A0A4Y7SMY0	A0A4Y7U0G9	P-loop containing nucleoside triphosphate hydrolase protein.	SP-RING-type domain-containing protein.	0.997

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

36

average node degree:

6.55

avg. local clustering coefficient:

0.731

expected number of edges:

13

PPI enrichment p-value:

2.04e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:1902600

Proton transmembrane transport

9 of 18

2.12

5.82

7.30e-15

GO:0044271

Cellular nitrogen compound biosynthetic process

9 of 335

0.85

4.91e-06

GO:1901566

Organonitrogen compound biosynthetic process

9 of 391

0.78

0.74

1.63e-05

GO:0044237

Cellular metabolic process

10 of 1088

0.38

0.3

0.0081

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0015078

Proton transmembrane transporter activity

9 of 19

2.09

5.77

5.63e-15

GO:0046933

Proton-transporting ATP synthase activity, rotational mechanism

8 of 13

2.21

5.77

7.94e-14

GO:0046961

Proton-transporting ATPase activity, rotational mechanism

3 of 9

1.94

1.72

0.00033

GO:0022857

Transmembrane transporter activity

10 of 199

1.12

1.53

1.58e-09

GO:0015399

Primary active transmembrane transporter activity

4 of 81

1.11

0.8

0.0053

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0045259

Proton-transporting ATP synthase complex

9 of 11

2.33

7.35

3.11e-17

GO:0045261

Proton-transporting ATP synthase complex, catalytic core F(1)

5 of 6

2.34

4.16

4.04e-09

GO:0045263

Proton-transporting ATP synthase complex, coupling factor F(o)

4 of 4

2.42

3.52

1.44e-07

GO:0005886

Plasma membrane

9 of 575

0.61

0.51

0.00028

GO:0005622

Intracellular anatomical structure

10 of 1035

0.4

0.33

0.0032

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:237

Proton-transporting ATP synthase complex

8 of 8

2.42

6.61

1.21e-14

CL:69

Ribosome, and Proton-transporting ATP synthase complex

9 of 93

1.4

2.31

1.06e-09

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

mas00190

Oxidative phosphorylation

9 of 19

2.09

5.99

9.99e-16

mas01100

Metabolic pathways

9 of 486

0.68

0.58

0.00024

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0045259

Proton-transporting ATP synthase complex

8 of 9

2.37

6.66

4.37e-15

GOCC:0016469

Proton-transporting two-sector ATPase complex

9 of 16

2.17

6.31

7.65e-16

GOCC:0045261

Proton-transporting ATP synthase complex, catalytic core F(1)

5 of 5

2.42

4.22

4.48e-09

GOCC:0033177

Proton-transporting two-sector ATPase complex, proton-transporting domain

4 of 7

2.17

2.87

1.60e-06

GOCC:0045263

Proton-transporting ATP synthase complex, coupling factor F(o)

3 of 4

2.29

2.23

5.26e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0375

Hydrogen ion transport

8 of 12

2.24

6.1

1.68e-14

KW-0066

ATP synthesis

8 of 12

2.24

6.1

1.68e-14

KW-0406

Ion transport

9 of 23

2.01

5.42

7.76e-15

KW-0139

CF(1)

5 of 5

2.42

4.28

3.33e-09

KW-0138

CF(0)

3 of 3

2.42

2.45

2.24e-05

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00137

ATP synthase subunit C

2 of 2

2.42

0.81

0.0339

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