STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
A0A4Y7SFD1Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (689 aa)    
Predicted Functional Partners:
A0A4Y7TQ96
Autophagy-related protein.
   
 0.991
A0A4Y7STE9
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.
    
 0.986
A0A4Y7TQR6
HECT domain-containing protein.
    
 0.977
A0A4Y7T3H7
Autophagy-related protein 3.
  
 
 0.957
A0A4Y7T7V8
Ubiquitin conjugating enzyme family protein.
  
 0.955
A0A4Y7TWV2
UBIQUITIN_CONJUGAT_2 domain-containing protein.
  
 0.955
A0A4Y7RPP8
Uncharacterized protein.
    
 0.948
A0A4Y7TTG9
Uncharacterized protein.
    
 0.948
A0A4Y7TXZ8
Putative ubiquitin conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.931
A0A4Y7T7Q9
Autophagy_act_C domain-containing protein.
   
 0.917
Your Current Organism:
Coprinellus micaceus
NCBI taxonomy Id: 71717
Other names: C. micaceus, Coprinus micaceus
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