STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A4Y7SWZ3Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (370 aa)    
Predicted Functional Partners:
A0A4Y7TMG6
DNA polymerase eta.
   
 0.997
A0A4Y7TP57
Uncharacterized protein.
   
 0.997
A0A4Y7TQ77
P-loop containing nucleoside triphosphate hydrolase protein.
  
 0.996
A0A4Y7TK76
P-loop containing nucleoside triphosphate hydrolase protein.
  
 0.992
A0A4Y7SP53
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
   
 0.990
A0A4Y7TXQ9
P-loop containing nucleoside triphosphate hydrolase protein.
  
 0.990
A0A4Y7TG69
DNA replication factor.
  
 0.987
A0A4Y7T4Q2
DNA polymerase.
  
 0.986
A0A4Y7TRB7
DNA polymerase subunit delta-2.
   
 0.984
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.983
Your Current Organism:
Coprinellus micaceus
NCBI taxonomy Id: 71717
Other names: C. micaceus, Coprinus micaceus
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.