STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A4Y7TXE7TPR_REGION domain-containing protein. (584 aa)    
Predicted Functional Partners:
GET3
ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]
   
 0.872
A0A4Y7TB30
RNA polymerase II accessory factor.
    
 0.866
A0A4Y7THU1
Leo1-domain-containing protein.
    
 0.865
A0A4Y7TKJ7
TPR-like protein.
    
 0.865
A0A4Y7TKF0
Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
    
 0.863
A0A4Y7T8Y8
Anaphase promoting complex subunit 1.
    
 0.862
A0A4Y7TI30
Uncharacterized protein.
    
 0.862
A0A4Y7TLH0
Uncharacterized protein.
    
 0.862
A0A4Y7TP31
ANAPC5 domain-containing protein.
    
 0.861
A0A4Y7T5C9
RING/U-box.
    
 0.860
Your Current Organism:
Coprinellus micaceus
NCBI taxonomy Id: 71717
Other names: C. micaceus, Coprinus micaceus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.