STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pheAPFAM: Prephenate dehydratase; ACT domain. (288 aa)    
Predicted Functional Partners:
AGA58633.1
ACT domain-containing protein; PFAM: ACT domain; Belongs to the UPF0735 family.
  
 
 0.977
AGA57969.1
PFAM: Prephenate dehydrogenase; ACT domain.
 
 0.966
AGA57977.1
Monofunctional chorismate mutase, clade 1; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
 
  
 0.937
hisC
PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
 0.933
AGA58786.1
PFAM: DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase.
 
  
 0.933
AGA57289.1
PFAM: Aminotransferase class I and II.
 
  
 0.899
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
 
     0.888
ilvE
Branched-chain amino acid aminotransferase, group I; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
 
   
 0.832
katG
Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
     
  0.800
AGA58632.1
PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain.
 
   
 0.795
Your Current Organism:
Thermobacillus composti
NCBI taxonomy Id: 717605
Other names: T. composti KWC4, Thermobacillus composti DSM 18247, Thermobacillus composti KWC4, Thermobacillus composti str. KWC4, Thermobacillus composti strain KWC4, Thermobacillus sp. KWC4
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