STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGA59025.1PFAM: DNA alkylation repair enzyme. (243 aa)    
Predicted Functional Partners:
AGA59110.1
O-6-methylguanine DNA methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
      0.858
AGA59026.1
PFAM: Activator of Hsp90 ATPase homolog 1-like protein.
       0.581
AGA56481.1
Putative virion core protein (lumpy skin disease virus); PFAM: SPFH domain / Band 7 family.
  
     0.527
AGA59024.1
PFAM: Uncharacterised protein family (UPF0236).
       0.507
AGA56483.1
PFAM: TFIIB zinc-binding; manually curated.
  
     0.502
AGA58896.1
DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit; Domain of unknown function (DUF3427).
  
   
 0.481
AGA56482.1
Beta-propeller domain-containing protein, methanol dehydrogenase; PFAM: Domain of unknown function (DUF477).
  
     0.434
nnrE
yjeF-like protein, hydroxyethylthiazole kinase-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate d [...]
 
     0.416
AGA56593.1
Hypothetical protein.
  
     0.410
Your Current Organism:
Thermobacillus composti
NCBI taxonomy Id: 717605
Other names: T. composti KWC4, Thermobacillus composti DSM 18247, Thermobacillus composti KWC4, Thermobacillus composti str. KWC4, Thermobacillus composti strain KWC4, Thermobacillus sp. KWC4
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