Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CLS_19730Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase./Histidine kinase. (347 aa)    
Predicted Functional Partners:
CLS_19720
Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain.
 
  
 0.924
CLS_19740
Monosaccharide ABC transporter ATP-binding protein, CUT2 family (TC 3.A.1.2.-).
 
    0.834
CLS_19710
Sugar kinases, ribokinase family.
       0.689
CLS_19680
Monosaccharide ABC transporter substrate-binding protein, CUT2 family (TC 3.A.1.2.-).
 
   0.655
CLS_21000
Two component transcriptional regulator, AraC family.
 
  
 0.568
CLS_19700
ABC-type sugar transport system, auxiliary component.
       0.516
CLS_30440
Monosaccharide ABC transporter substrate-binding protein, CUT2 family (TC 3.A.1.2.-).
 
   0.462
CLS_10480
AraC-type DNA-binding domain-containing proteins.
 
  
 0.450
CLS_20610
AraC-type DNA-binding domain-containing proteins.
 
  
 0.446
CLS_11350
ABC-type sugar transport system, periplasmic component.
 
   0.440
Your Current Organism:
Clostridium saccharolyticum K10
NCBI taxonomy Id: 717608
Other names: Clostridium cf. saccharolyticum K10, [. cf. saccharolyticum K10, [Clostridium] cf. saccharolyticum K10
Server load: low (14%) [HD]