Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CLS_32020Glucose PTS system EIICBA or EIICB component; PTS system IIA component, Glc family (TC 4.A.1)/PTS system IIB component, Glc family (TC 4.A.1)/PTS system IIC component, Glc family (TC 4.A.1). (756 aa)    
Predicted Functional Partners:
CLS_00300
Glucokinase.
  
 0.990
CLS_19690
Transcriptional regulator/sugar kinase.
  
 0.990
CLS_12640
Uncharacterized protein; PTS system beta-glucoside-specific IIA component, Glc family (TC 4.A.1.2.6)/PTS system beta-glucoside-specific IIB component, Glc family (TC 4.A.1.2.6)/PTS system beta-glucoside-specific IIC component, Glc family (TC 4.A.1.2.6).
 
 
0.982
CLS_24490
PTS system IIA component, Glc family (TC 4.A.1).
 
 
0.981
CLS_32010
Transcriptional antiterminator, BglG family.
 
 
 0.965
CLS_03320
Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.964
CLS_03310
Phosphotransferase System HPr (HPr) Family.
 
 0.956
CLS_24500
Phosphotransferase system, HPr-related proteins.
 
 0.956
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.955
CLS_17630
PTS HPr component phosphorylation site.
  
 0.949
Your Current Organism:
Clostridium saccharolyticum K10
NCBI taxonomy Id: 717608
Other names: Clostridium cf. saccharolyticum K10, [. cf. saccharolyticum K10, [Clostridium] cf. saccharolyticum K10
Server load: medium (58%) [HD]