Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CLS_32090Signal transduction histidine kinase. (885 aa)    
Predicted Functional Partners:
CLS_04350
Diguanylate cyclase (GGDEF) domain.
 
 
 0.985
CLS_03510
PAS domain S-box/diguanylate cyclase (GGDEF) domain.
 
 
 0.984
CLS_24450
Hpt domain.
 
 
 0.979
CLS_19020
His Kinase A (phosphoacceptor) domain./Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 
0.970
CLS_08570
Hypothetical protein.
  
 
 0.963
CLS_24440
Response regulator containing a CheY-like receiver domain and an HD-GYP domain.
 
 
 0.962
CLS_19100
Diguanylate cyclase (GGDEF) domain.
  
 0.926
CLS_30550
FOG: EAL domain.
  
 0.925
CLS_19990
Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.
   
 0.884
CLS_36800
Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.
   
 0.884
Your Current Organism:
Clostridium saccharolyticum K10
NCBI taxonomy Id: 717608
Other names: Clostridium cf. saccharolyticum K10, [. cf. saccharolyticum K10, [Clostridium] cf. saccharolyticum K10
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