STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppnPUPF0345 protein yaiE; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (103 aa)    
Predicted Functional Partners:
ADZ91005.1
Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
     
 0.902
ADZ89757.1
2',3'-cyclic-nucleotide 2'-phosphodiesterase; KEGG: mmw:Mmwyl1_4082 5'-nucleotidase domain-containing protein; PFAM: 5'-Nucleotidase, C-terminal; Metallo-dependent phosphatase; Belongs to the 5'-nucleotidase family.
     
  0.900
psuG
Pseudouridine-5'-phosphate glycosidase; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.
     
  0.900
ADZ89789.1
Cytosine deaminase; KEGG: mmw:Mmwyl1_1583 N-isopropylammelide isopropylaminohydrolase; PFAM: Amidohydrolase 3.
    
  0.900
ADZ89818.1
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
     
  0.900
ADZ89864.1
Uridine kinase; KEGG: mmw:Mmwyl1_3961 phosphoribulokinase/uridine kinase; PFAM: Phosphoribulokinase/uridine kinase.
     
 0.900
ADZ89879.1
Conserved hypothetical protein CHP00730; PFAM: Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG; KEGG: mmw:Mmwyl1_3796 hypothetical protein.
     
  0.900
surE
Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.900
rutA
Pyrimidine utilization protein A; Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate.
     
  0.900
ADZ90638.1
KEGG: amc:MADE_00765 NAD(P)H-flavin oxidoreductase; PFAM: Flavin reductase-like, FMN-binding; SMART: Flavin reductase-like, FMN-binding.
     
  0.900
Your Current Organism:
Marinomonas mediterranea
NCBI taxonomy Id: 717774
Other names: M. mediterranea MMB-1, Marinomonas mediterranea MMB-1, Marinomonas mediterranea str. MMB-1, Marinomonas mediterranea strain MMB-1
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