STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (283 aa)    
Predicted Functional Partners:
yidC
Membrane protein oxaA; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
 
  
 0.877
ADZ89992.1
PTSINtr with GAF domain, PtsP; SMART: GAF; TIGRFAM: Phosphoenolpyruvate-protein phosphotransferase; KEGG: mmw:Mmwyl1_3747 phosphoenolpyruvate-protein phosphotransferase PtsP; PFAM: PEP-utilising enzyme; Phosphotransferase system, PEP-utilising enzyme, N-terminal; GAF; PEP-utilising enzyme, mobile domain; Belongs to the PEP-utilizing enzyme family.
       0.803
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
    0.764
trpA-2
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
    0.764
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
    0.751
trpB-2
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
    0.751
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 0.699
gpsA
KEGG: mmw:Mmwyl1_2121 glycerol-3-phosphate dehydrogenase (NAD(P)(+)); HAMAP: Glycerol-3-phosphate dehydrogenase, NAD-dependent; PFAM: Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal; Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
  
 0.687
lspA
Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
 
   
 0.680
ADZ89848.1
NADH dehydrogenase (quinone); KEGG: mmw:Mmwyl1_3982 putative monovalent cation/H+ antiporter subunit A; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; NADH:ubiquinone oxidoreductase, chain 5/L, N-terminal; Na+/H+ antiporter MnhB subunit-related protein.
  
    0.651
Your Current Organism:
Marinomonas mediterranea
NCBI taxonomy Id: 717774
Other names: M. mediterranea MMB-1, Marinomonas mediterranea MMB-1, Marinomonas mediterranea str. MMB-1, Marinomonas mediterranea strain MMB-1
Server load: low (24%) [HD]