node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADZ90347.1 | rlpA | Marme_1072 | Marme_1478 | PFAM: Surface presentation of antigen (SpoA); KEGG: pmy:Pmen_0045 surface presentation of antigens (SpoA) protein. | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.721 |
ADZ90744.1 | ADZ90746.1 | Marme_1477 | Marme_1479 | KEGG: mmw:Mmwyl1_2846 lytic murein transglycosylase B. | Beta-lactamase; PFAM: Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal; Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; KEGG: mmw:Mmwyl1_2844 serine-type D-Ala-D-Ala carboxypeptidase; SMART: Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; Belongs to the peptidase S11 family. | 0.754 |
ADZ90744.1 | ADZ91783.1 | Marme_1477 | Marme_2551 | KEGG: mmw:Mmwyl1_2846 lytic murein transglycosylase B. | Cell wall hydrolase/autolysin; KEGG: mmw:Mmwyl1_2635 N-acetylmuramoyl-L-alanine amidase; PFAM: Cell wall hydrolase/autolysin, catalytic; Peptidoglycan-binding lysin domain; SMART: Cell wall hydrolase/autolysin, catalytic; Peptidoglycan-binding Lysin subgroup. | 0.426 |
ADZ90744.1 | mrdA | Marme_1477 | Marme_1475 | KEGG: mmw:Mmwyl1_2846 lytic murein transglycosylase B. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.918 |
ADZ90744.1 | mrdB | Marme_1477 | Marme_1476 | KEGG: mmw:Mmwyl1_2846 lytic murein transglycosylase B. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.874 |
ADZ90744.1 | nadD | Marme_1477 | Marme_1472 | KEGG: mmw:Mmwyl1_2846 lytic murein transglycosylase B. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.732 |
ADZ90744.1 | proA | Marme_1477 | Marme_1471 | KEGG: mmw:Mmwyl1_2846 lytic murein transglycosylase B. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.732 |
ADZ90744.1 | rlmH | Marme_1477 | Marme_1474 | KEGG: mmw:Mmwyl1_2846 lytic murein transglycosylase B. | Ribosomal RNA large subunit methyltransferase H; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.817 |
ADZ90744.1 | rlpA | Marme_1477 | Marme_1478 | KEGG: mmw:Mmwyl1_2846 lytic murein transglycosylase B. | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.919 |
ADZ90744.1 | rsfS | Marme_1477 | Marme_1473 | KEGG: mmw:Mmwyl1_2846 lytic murein transglycosylase B. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.800 |
ADZ90746.1 | ADZ90744.1 | Marme_1479 | Marme_1477 | Beta-lactamase; PFAM: Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal; Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; KEGG: mmw:Mmwyl1_2844 serine-type D-Ala-D-Ala carboxypeptidase; SMART: Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; Belongs to the peptidase S11 family. | KEGG: mmw:Mmwyl1_2846 lytic murein transglycosylase B. | 0.754 |
ADZ90746.1 | ADZ91783.1 | Marme_1479 | Marme_2551 | Beta-lactamase; PFAM: Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal; Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; KEGG: mmw:Mmwyl1_2844 serine-type D-Ala-D-Ala carboxypeptidase; SMART: Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; Belongs to the peptidase S11 family. | Cell wall hydrolase/autolysin; KEGG: mmw:Mmwyl1_2635 N-acetylmuramoyl-L-alanine amidase; PFAM: Cell wall hydrolase/autolysin, catalytic; Peptidoglycan-binding lysin domain; SMART: Cell wall hydrolase/autolysin, catalytic; Peptidoglycan-binding Lysin subgroup. | 0.456 |
ADZ90746.1 | mrdA | Marme_1479 | Marme_1475 | Beta-lactamase; PFAM: Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal; Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; KEGG: mmw:Mmwyl1_2844 serine-type D-Ala-D-Ala carboxypeptidase; SMART: Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; Belongs to the peptidase S11 family. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.911 |
ADZ90746.1 | mrdB | Marme_1479 | Marme_1476 | Beta-lactamase; PFAM: Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal; Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; KEGG: mmw:Mmwyl1_2844 serine-type D-Ala-D-Ala carboxypeptidase; SMART: Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; Belongs to the peptidase S11 family. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.799 |
ADZ90746.1 | nadD | Marme_1479 | Marme_1472 | Beta-lactamase; PFAM: Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal; Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; KEGG: mmw:Mmwyl1_2844 serine-type D-Ala-D-Ala carboxypeptidase; SMART: Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; Belongs to the peptidase S11 family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.587 |
ADZ90746.1 | proA | Marme_1479 | Marme_1471 | Beta-lactamase; PFAM: Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal; Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; KEGG: mmw:Mmwyl1_2844 serine-type D-Ala-D-Ala carboxypeptidase; SMART: Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; Belongs to the peptidase S11 family. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.577 |
ADZ90746.1 | rlmH | Marme_1479 | Marme_1474 | Beta-lactamase; PFAM: Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal; Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; KEGG: mmw:Mmwyl1_2844 serine-type D-Ala-D-Ala carboxypeptidase; SMART: Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; Belongs to the peptidase S11 family. | Ribosomal RNA large subunit methyltransferase H; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.777 |
ADZ90746.1 | rlpA | Marme_1479 | Marme_1478 | Beta-lactamase; PFAM: Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal; Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; KEGG: mmw:Mmwyl1_2844 serine-type D-Ala-D-Ala carboxypeptidase; SMART: Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; Belongs to the peptidase S11 family. | Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.750 |
ADZ90746.1 | rsfS | Marme_1479 | Marme_1473 | Beta-lactamase; PFAM: Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal; Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; KEGG: mmw:Mmwyl1_2844 serine-type D-Ala-D-Ala carboxypeptidase; SMART: Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; Belongs to the peptidase S11 family. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.651 |
ADZ91783.1 | ADZ90744.1 | Marme_2551 | Marme_1477 | Cell wall hydrolase/autolysin; KEGG: mmw:Mmwyl1_2635 N-acetylmuramoyl-L-alanine amidase; PFAM: Cell wall hydrolase/autolysin, catalytic; Peptidoglycan-binding lysin domain; SMART: Cell wall hydrolase/autolysin, catalytic; Peptidoglycan-binding Lysin subgroup. | KEGG: mmw:Mmwyl1_2846 lytic murein transglycosylase B. | 0.426 |