STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ91085.1KEGG: mmw:Mmwyl1_1982 DNA-directed DNA polymerase; PFAM: DNA-repair protein, UmuC-like. (423 aa)    
Predicted Functional Partners:
ADZ91084.1
PFAM: Peptidase S24/S26A/S26B, conserved region; KEGG: mmw:Mmwyl1_1981 putative prophage repressor; Belongs to the peptidase S24 family.
 
 
 0.977
ADZ89308.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.884
ADZ91386.1
KEGG: mmw:Mmwyl1_2210 DNA polymerase II; PFAM: DNA-directed DNA polymerase, family B, conserved region; DNA-directed DNA polymerase, family B, exonuclease domain; SMART: DNA-directed DNA polymerase, family B.
   
 0.845
ADZ91425.1
KEGG: gpb:HDN1F_12710 hypothetical protein.
  
  
 0.773
ADZ92098.1
Transcriptional regulator, AraC family; KEGG: ppr:PBPRB0209 Ada family regulatory protein; PFAM: AlkA, N-terminal; Ada DNA repair, metal-binding; HTH transcriptional regulator, AraC; SMART: Helix-turn-helix, AraC type, DNA binding domain.
  
 
 0.679
lexA
SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
 
 
 0.651
ADZ91071.1
Phage repressor like transcriptional regulator, XRE family; KEGG: mmw:Mmwyl1_2471 putative prophage repressor; PFAM: Peptidase S24/S26A/S26B, conserved region; Helix-turn-helix type 3; SMART: Helix-turn-helix type 3.
 
 
 0.649
recA
Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.623
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.604
ADZ91083.1
PFAM: KilA, N-terminal/APSES-type HTH, DNA-binding; KEGG: vvu:VV2_0650 hypothetical protein.
       0.592
Your Current Organism:
Marinomonas mediterranea
NCBI taxonomy Id: 717774
Other names: M. mediterranea MMB-1, Marinomonas mediterranea MMB-1, Marinomonas mediterranea str. MMB-1, Marinomonas mediterranea strain MMB-1
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