STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ91485.1KEGG: mmw:Mmwyl1_2123 phosphohistidine phosphatase, SixA; PFAM: Histidine phosphatase superfamily, clade-1; SMART: Histidine phosphatase superfamily, clade-1. (158 aa)    
Predicted Functional Partners:
ADZ91484.1
PFAM: Alpha/beta hydrolase fold-1; KEGG: mmw:Mmwyl1_2124 alpha/beta hydrolase fold.
       0.742
ADZ91486.1
KEGG: mmw:Mmwyl1_2122 hypothetical protein.
  
    0.697
ADZ91299.1
PFAM: Protein of unknown function DUF1315; KEGG: mmw:Mmwyl1_2165 hypothetical protein.
  
     0.668
ADZ91728.1
PFAM: Protein of unknown function DUF446; KEGG: mmw:Mmwyl1_1750 hypothetical protein.
  
     0.660
gpsA
KEGG: mmw:Mmwyl1_2121 glycerol-3-phosphate dehydrogenase (NAD(P)(+)); HAMAP: Glycerol-3-phosphate dehydrogenase, NAD-dependent; PFAM: Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal; Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
       0.647
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
     0.632
ADZ91508.1
tRNA-hydroxylase; PFAM: tRNA--hydroxylase; KEGG: mmw:Mmwyl1_2099 tRNA--hydroxylase.
  
     0.590
ADZ91483.1
KEGG: mmw:Mmwyl1_2125 hypothetical protein.
       0.588
ADZ91298.1
PFAM: Peptidase S54, rhomboid domain; KEGG: mmw:Mmwyl1_2164 rhomboid family protein.
 
     0.566
trmA
tRNA (uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
  
     0.511
Your Current Organism:
Marinomonas mediterranea
NCBI taxonomy Id: 717774
Other names: M. mediterranea MMB-1, Marinomonas mediterranea MMB-1, Marinomonas mediterranea str. MMB-1, Marinomonas mediterranea strain MMB-1
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