STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADZ92530.1Cystathionine beta-lyase; KEGG: mmw:Mmwyl1_3512 class I/II aminotransferase; PFAM: Aminotransferase, class I/classII. (398 aa)    
Predicted Functional Partners:
ADZ93172.1
PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; KEGG: mmw:Mmwyl1_3697 cystathionine gamma-synthase.
 
 
 0.942
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
 
 
 0.940
ADZ91185.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.936
ADZ90077.1
TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: mmw:Mmwyl1_1496 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme.
   
 0.929
ADZ91057.1
TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; KEGG: mmw:Mmwyl1_2520 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.921
ADZ91148.1
2-hydroxypropyl-CoM lyase; KEGG: cps:CPS_1151 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; PFAM: Methionine synthase, vitamin-B12 independent.
    
 0.903
luxS
Quorum-sensing autoinducer 2 (AI-2), LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
     
  0.900
ADZ92503.1
3-mercaptopyruvate sulfurtransferase; PFAM: Rhodanese-like; KEGG: mmw:Mmwyl1_3485 rhodanese domain-containing protein; SMART: Rhodanese-like.
     
  0.900
ADZ93380.1
Aspartate transaminase; KEGG: mmw:Mmwyl1_4445 aromatic amino acid aminotransferase; PFAM: Aminotransferase, class I/classII.
     
  0.900
ADZ89974.1
KEGG: mmw:Mmwyl1_3765 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT.
    
 0.829
Your Current Organism:
Marinomonas mediterranea
NCBI taxonomy Id: 717774
Other names: M. mediterranea MMB-1, Marinomonas mediterranea MMB-1, Marinomonas mediterranea str. MMB-1, Marinomonas mediterranea strain MMB-1
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