Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AL1_27770Predicted Zn-dependent peptidases. (404 aa)    
Predicted Functional Partners:
nuoD
NADH dehydrogenase subunit C /NADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.
   
 
 0.964
AL1_27790
Predicted O-methyltransferase.
  
    0.814
AL1_27780
Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.
  
    0.784
AL1_27800
Predicted pyrophosphatase.
       0.783
AL1_13410
Predicted Zn-dependent peptidases.
  
     0.682
AL1_27760
Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
       0.588
AL1_13420
Predicted Zn-dependent peptidases.
 
    
0.514
AL1_25980
Ni,Fe-hydrogenase III large subunit.
   
 
 0.514
nuoB
NADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
   
 
 0.510
AL1_26220
Nitroreductase.
  
 
 0.500
Your Current Organism:
Alistipes shahii
NCBI taxonomy Id: 717959
Other names: A. shahii WAL 8301, Alistipes shahii WAL 8301, Alistipes shahii str. WAL 8301, Alistipes shahii strain WAL 8301, Alistipes sp. WAL 8301
Server load: low (14%) [HD]