rnhB protein (Faecalitalea cylindroides) - STRING interaction network

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Score

rnhB

RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (202 aa)

Predicted Functional Partners:

EC1_13890

0.911

EC1_09150

0.764

acpP

0.762

dnaJ

0.733

EC1_03860

0.726

topA

0.718

EC1_17090

0.709

polA

0.674

EC1_00390

0.674

trmD

0.659

Your Current Organism:

Faecalitalea cylindroides

NCBI taxonomy Id: 717960
Other names: Eubacterium cylindroides T2-87, F. cylindroides T2-87, Faecalitalea cylindroides T2-87

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EC1_00390	EC1_13890	EC1_00390	EC1_13890	5'-3' exonuclease (including N-terminal domain of PolI).	DNA polymerase sliding clamp subunit (PCNA homolog).	0.999
EC1_00390	acpP	EC1_00390	EC1_01360	5'-3' exonuclease (including N-terminal domain of PolI).	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.	0.682
EC1_00390	dnaJ	EC1_00390	EC1_08550	5'-3' exonuclease (including N-terminal domain of PolI).	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.557
EC1_00390	polA	EC1_00390	EC1_00380	5'-3' exonuclease (including N-terminal domain of PolI).	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.999
EC1_00390	rnhB	EC1_00390	EC1_03870	5'-3' exonuclease (including N-terminal domain of PolI).	RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.674
EC1_00390	topA	EC1_00390	EC1_03850	5'-3' exonuclease (including N-terminal domain of PolI).	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.908
EC1_00390	trmD	EC1_00390	EC1_08980	5'-3' exonuclease (including N-terminal domain of PolI).	tRNA (Guanine37-N(1)-) methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.	0.533
EC1_03860	rnhB	EC1_03860	EC1_03870	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake.	RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.726
EC1_03860	topA	EC1_03860	EC1_03850	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.890
EC1_09150	rnhB	EC1_09150	EC1_03870	Alpha-phosphoglucomutase.	RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.764
EC1_13890	EC1_00390	EC1_13890	EC1_00390	DNA polymerase sliding clamp subunit (PCNA homolog).	5'-3' exonuclease (including N-terminal domain of PolI).	0.999
EC1_13890	acpP	EC1_13890	EC1_01360	DNA polymerase sliding clamp subunit (PCNA homolog).	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.	0.438
EC1_13890	polA	EC1_13890	EC1_00380	DNA polymerase sliding clamp subunit (PCNA homolog).	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.999
EC1_13890	rnhB	EC1_13890	EC1_03870	DNA polymerase sliding clamp subunit (PCNA homolog).	RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.911
EC1_13890	topA	EC1_13890	EC1_03850	DNA polymerase sliding clamp subunit (PCNA homolog).	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.733
EC1_17090	acpP	EC1_17090	EC1_01360	Hypothetical protein.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.	0.993
EC1_17090	dnaJ	EC1_17090	EC1_08550	Hypothetical protein.	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.794
EC1_17090	rnhB	EC1_17090	EC1_03870	Hypothetical protein.	RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.709
EC1_17090	topA	EC1_17090	EC1_03850	Hypothetical protein.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.549
acpP	EC1_00390	EC1_01360	EC1_00390	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.	5'-3' exonuclease (including N-terminal domain of PolI).	0.682