| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FP2_01840 | ddl | FP2_01840 | FP2_02400 | UDP-N-acetylglucosamine enolpyruvyl transferase. | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.654 |
| FP2_01840 | murB | FP2_01840 | FP2_07560 | UDP-N-acetylglucosamine enolpyruvyl transferase. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.983 |
| FP2_01840 | murC | FP2_01840 | FP2_23390 | UDP-N-acetylglucosamine enolpyruvyl transferase. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.880 |
| FP2_01840 | murD | FP2_01840 | FP2_20780 | UDP-N-acetylglucosamine enolpyruvyl transferase. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.815 |
| FP2_01840 | murF | FP2_01840 | FP2_25160 | UDP-N-acetylglucosamine enolpyruvyl transferase. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.815 |
| FP2_01840 | murG | FP2_01840 | FP2_25190 | UDP-N-acetylglucosamine enolpyruvyl transferase. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.793 |
| FP2_07570 | FP2_07590 | FP2_07570 | FP2_07590 | Predicted P-loop-containing kinase; Displays ATPase and GTPase activities. | DNA polymerase III catalytic subunit, DnaE type. | 0.785 |
| FP2_07570 | hprK | FP2_07570 | FP2_07550 | Predicted P-loop-containing kinase; Displays ATPase and GTPase activities. | Hpr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] | 0.725 |
| FP2_07570 | murB | FP2_07570 | FP2_07560 | Predicted P-loop-containing kinase; Displays ATPase and GTPase activities. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.782 |
| FP2_07570 | whiA | FP2_07570 | FP2_07580 | Predicted P-loop-containing kinase; Displays ATPase and GTPase activities. | Conserved hypothetical protein; Involved in cell division and chromosome segregation. | 0.883 |
| FP2_07590 | FP2_07570 | FP2_07590 | FP2_07570 | DNA polymerase III catalytic subunit, DnaE type. | Predicted P-loop-containing kinase; Displays ATPase and GTPase activities. | 0.785 |
| FP2_07590 | hprK | FP2_07590 | FP2_07550 | DNA polymerase III catalytic subunit, DnaE type. | Hpr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] | 0.701 |
| FP2_07590 | murB | FP2_07590 | FP2_07560 | DNA polymerase III catalytic subunit, DnaE type. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.768 |
| FP2_07590 | whiA | FP2_07590 | FP2_07580 | DNA polymerase III catalytic subunit, DnaE type. | Conserved hypothetical protein; Involved in cell division and chromosome segregation. | 0.818 |
| ddl | FP2_01840 | FP2_02400 | FP2_01840 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylglucosamine enolpyruvyl transferase. | 0.654 |
| ddl | murB | FP2_02400 | FP2_07560 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.984 |
| ddl | murC | FP2_02400 | FP2_23390 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.977 |
| ddl | murD | FP2_02400 | FP2_20780 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.771 |
| ddl | murF | FP2_02400 | FP2_25160 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.993 |
| ddl | murG | FP2_02400 | FP2_25190 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.896 |