Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FP2_07650Stage III sporulation protein AC/AD protein family. (121 aa)    
Predicted Functional Partners:
FP2_07660
Stage III sporulation protein AE (spore_III_AE).
 
  
 0.982
FP2_07640
Stage III sporulation protein AC.
 
  
 0.981
FP2_07680
Hypothetical protein.
  
  
 0.899
FP2_07690
Hypothetical protein.
 
  
 0.860
FP2_07670
Hypothetical protein.
       0.773
FP2_07620
Uncharacterized protein conserved in bacteria.
 
  
 0.757
FP2_07700
Uncharacterized protein conserved in bacteria.
 
    0.605
nusB
Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
       0.452
FP2_12180
Stage II sporulation protein P.
  
   
 0.440
FP2_08180
Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
 
   
 0.421
Your Current Organism:
Faecalibacterium prausnitzii L26
NCBI taxonomy Id: 718252
Other names: F. prausnitzii L2-6, Faecalibacterium prausnitzii L2-6, Faecalibacterium prausnitzii str. L2-6, Faecalibacterium prausnitzii strain L2-6, butyrate-producing bacterium L2-6
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