FP2_09540 protein (Faecalibacterium prausnitzii L26)

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FP2_09540

tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (339 aa)

Predicted Functional Partners:

truA

0.593

polA

0.489

FP2_09530

0.487

FP2_05830

0.462

guaA

0.430

FP2_15460

0.417

mfd

0.401

Your Current Organism:

Faecalibacterium prausnitzii L26

NCBI taxonomy Id: 718252
Other names: F. prausnitzii L2-6, Faecalibacterium prausnitzii L2-6, Faecalibacterium prausnitzii str. L2-6, Faecalibacterium prausnitzii strain L2-6, butyrate-producing bacterium L2-6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FP2_05830	FP2_09540	FP2_05830	FP2_09540	tRNA and rRNA cytosine-C5-methylases.	tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	0.462
FP2_05830	FP2_15460	FP2_05830	FP2_15460	tRNA and rRNA cytosine-C5-methylases.	Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.	0.813
FP2_05830	guaA	FP2_05830	FP2_21030	tRNA and rRNA cytosine-C5-methylases.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.429
FP2_09530	FP2_09540	FP2_09530	FP2_09540	Hypothetical protein.	tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	0.487
FP2_09540	FP2_05830	FP2_09540	FP2_05830	tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	tRNA and rRNA cytosine-C5-methylases.	0.462
FP2_09540	FP2_09530	FP2_09540	FP2_09530	tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	Hypothetical protein.	0.487
FP2_09540	FP2_15460	FP2_09540	FP2_15460	tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.	0.417
FP2_09540	guaA	FP2_09540	FP2_21030	tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.430
FP2_09540	mfd	FP2_09540	FP2_11240	tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.	0.401
FP2_09540	polA	FP2_09540	FP2_26340	tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.489
FP2_09540	truA	FP2_09540	FP2_22620	tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	Pseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.	0.593
FP2_15460	FP2_05830	FP2_15460	FP2_05830	Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.	tRNA and rRNA cytosine-C5-methylases.	0.813
FP2_15460	FP2_09540	FP2_15460	FP2_09540	Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.	tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	0.417
guaA	FP2_05830	FP2_21030	FP2_05830	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	tRNA and rRNA cytosine-C5-methylases.	0.429
guaA	FP2_09540	FP2_21030	FP2_09540	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	0.430
guaA	polA	FP2_21030	FP2_26340	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.738
mfd	FP2_09540	FP2_11240	FP2_09540	Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.	tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	0.401
mfd	polA	FP2_11240	FP2_26340	Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.724
mfd	truA	FP2_11240	FP2_22620	Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.	Pseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.	0.438
polA	FP2_09540	FP2_26340	FP2_09540	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	0.489

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