Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
FP2_09620Predicted membrane protein; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family. (199 aa)    
Predicted Functional Partners:
FP2_27460
Probable proton-coupled thiamine transporter YuaJ.
  
   
 0.504
FP2_22630
ABC-type cobalt transport system, permease component CbiQ and related transporters.
 
   
 0.500
ribBA
GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
   
  
 0.457
ecfA
ABC-type cobalt transport system, ATPase component; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
   
 0.452
FP2_16030
Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family.
  
     0.450
FP2_21320
3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase.
  
     0.417
FP2_17990
Predicted membrane protein.
  
   
 0.411
ecfA-2
ABC-type cobalt transport system, ATPase component; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
   
 0.402
Your Current Organism:
Faecalibacterium prausnitzii L26
NCBI taxonomy Id: 718252
Other names: F. prausnitzii L2-6, Faecalibacterium prausnitzii L2-6, Faecalibacterium prausnitzii str. L2-6, Faecalibacterium prausnitzii strain L2-6, butyrate-producing bacterium L2-6
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