Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
FP2_15310Exodeoxyribonuclease III. (250 aa)    
Predicted Functional Partners:
nth
Predicted EndoIII-related endonuclease; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
 0.993
FP2_01560
Ribosomal small subunit pseudouridine synthase A; Belongs to the pseudouridine synthase RsuA family.
  
    0.913
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.875
FP2_19920
birA, biotin-[acetyl-CoA-carboxylase] ligase region.
  
    0.821
birA
birA, biotin-[acetyl-CoA-carboxylase] ligase region; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
    0.821
FP2_05990
Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family.
  
    0.771
FP2_15320
Predicted membrane protein.
       0.770
FP2_15300
Putative efflux protein, MATE family.
       0.725
FP2_21020
DNA-3-methyladenine glycosylase II.
   
 0.659
FP2_21320
3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase.
   
 0.659
Your Current Organism:
Faecalibacterium prausnitzii L26
NCBI taxonomy Id: 718252
Other names: F. prausnitzii L2-6, Faecalibacterium prausnitzii L2-6, Faecalibacterium prausnitzii str. L2-6, Faecalibacterium prausnitzii strain L2-6, butyrate-producing bacterium L2-6
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