| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FP2_05350 | FP2_15380 | FP2_05350 | FP2_15380 | Aspartate carbamoyltransferase, regulatory subunit. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.927 |
| FP2_05350 | FP2_28170 | FP2_05350 | FP2_28170 | Aspartate carbamoyltransferase, regulatory subunit. | Ornithine carbamoyltransferase. | 0.809 |
| FP2_05350 | argG | FP2_05350 | FP2_28090 | Aspartate carbamoyltransferase, regulatory subunit. | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.900 |
| FP2_05350 | carA | FP2_05350 | FP2_15430 | Aspartate carbamoyltransferase, regulatory subunit. | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | 0.956 |
| FP2_05350 | carB | FP2_05350 | FP2_15440 | Aspartate carbamoyltransferase, regulatory subunit. | Carbamoyl-phosphate synthase large subunit. | 0.951 |
| FP2_05350 | pyrB | FP2_05350 | FP2_05360 | Aspartate carbamoyltransferase, regulatory subunit. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| FP2_05350 | pyrD | FP2_05350 | FP2_15410 | Aspartate carbamoyltransferase, regulatory subunit. | Dihydroorotate oxidase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. | 0.625 |
| FP2_15380 | FP2_05350 | FP2_15380 | FP2_05350 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Aspartate carbamoyltransferase, regulatory subunit. | 0.927 |
| FP2_15380 | FP2_28170 | FP2_15380 | FP2_28170 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Ornithine carbamoyltransferase. | 0.913 |
| FP2_15380 | carA | FP2_15380 | FP2_15430 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | 0.995 |
| FP2_15380 | carB | FP2_15380 | FP2_15440 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Carbamoyl-phosphate synthase large subunit. | 0.995 |
| FP2_15380 | purF | FP2_15380 | FP2_01470 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.428 |
| FP2_15380 | pyrB | FP2_15380 | FP2_05360 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| FP2_15380 | pyrD | FP2_15380 | FP2_15410 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Dihydroorotate oxidase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. | 0.998 |
| FP2_15380 | pyrE | FP2_15380 | FP2_15420 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Orotate phosphoribosyltransferase, Thermus family; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.947 |
| FP2_19280 | FP2_28170 | FP2_19280 | FP2_28170 | Glutamate synthase domain 2. | Ornithine carbamoyltransferase. | 0.490 |
| FP2_19280 | argG | FP2_19280 | FP2_28090 | Glutamate synthase domain 2. | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.556 |
| FP2_19280 | carA | FP2_19280 | FP2_15430 | Glutamate synthase domain 2. | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | 0.924 |
| FP2_19280 | carB | FP2_19280 | FP2_15440 | Glutamate synthase domain 2. | Carbamoyl-phosphate synthase large subunit. | 0.966 |
| FP2_19280 | purF | FP2_19280 | FP2_01470 | Glutamate synthase domain 2. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.942 |