Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FP2_26320CAAX amino terminal protease family. (277 aa)    
Predicted Functional Partners:
FP2_28730
Hypothetical protein.
  
    0.654
mprF
Uncharacterised protein family (UPF0104); Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
 
    0.579
FP2_24490
Fucose 4-O-acetylase and related acetyltransferases.
  
     0.578
FP2_06210
Predicted membrane protein.
  
    0.550
FP2_20490
Hypothetical protein.
  
     0.548
FP2_20480
Hypothetical protein.
  
     0.526
FP2_19170
Nitroreductase.
  
  
 0.500
FP2_26480
Nitroreductase.
  
  
 0.500
FP2_32490
Integral membrane protein (intg_mem_TP0381).
  
     0.496
FP2_10910
Uncharacterized protein conserved in bacteria C-term(DUF2220).
  
     0.481
Your Current Organism:
Faecalibacterium prausnitzii L26
NCBI taxonomy Id: 718252
Other names: F. prausnitzii L2-6, Faecalibacterium prausnitzii L2-6, Faecalibacterium prausnitzii str. L2-6, Faecalibacterium prausnitzii strain L2-6, butyrate-producing bacterium L2-6
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