tsaD protein (Faecalibacterium prausnitzii L26)

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tsaD

O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (335 aa)

Predicted Functional Partners:

FP2_25810

0.959

FP2_25800

0.944

polA

0.881

pheT

0.710

rsmA

0.708

FP2_30490

0.559

pheS

0.557

FP2_30760

0.548

FP2_11930

0.541

guaA

0.515

Your Current Organism:

Faecalibacterium prausnitzii L26

NCBI taxonomy Id: 718252
Other names: F. prausnitzii L2-6, Faecalibacterium prausnitzii L2-6, Faecalibacterium prausnitzii str. L2-6, Faecalibacterium prausnitzii strain L2-6, butyrate-producing bacterium L2-6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FP2_11930	tsaD	FP2_11930	FP2_26330	3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).	O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.	0.541
FP2_25800	FP2_25810	FP2_25800	FP2_25810	Conserved hypothetical nucleotide-binding protein.	Inactive homolog of metal-dependent proteases, putative molecular chaperone.	0.997
FP2_25800	pheT	FP2_25800	FP2_18680	Conserved hypothetical nucleotide-binding protein.	phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.	0.426
FP2_25800	polA	FP2_25800	FP2_26340	Conserved hypothetical nucleotide-binding protein.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.433
FP2_25800	tsaD	FP2_25800	FP2_26330	Conserved hypothetical nucleotide-binding protein.	O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.	0.944
FP2_25810	FP2_25800	FP2_25810	FP2_25800	Inactive homolog of metal-dependent proteases, putative molecular chaperone.	Conserved hypothetical nucleotide-binding protein.	0.997
FP2_25810	guaA	FP2_25810	FP2_21030	Inactive homolog of metal-dependent proteases, putative molecular chaperone.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.439
FP2_25810	pheT	FP2_25810	FP2_18680	Inactive homolog of metal-dependent proteases, putative molecular chaperone.	phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.	0.483
FP2_25810	tsaD	FP2_25810	FP2_26330	Inactive homolog of metal-dependent proteases, putative molecular chaperone.	O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.	0.959
FP2_30490	rsmA	FP2_30490	FP2_01630	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.	Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.	0.428
FP2_30490	tsaD	FP2_30490	FP2_26330	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.	O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.	0.559
FP2_30760	rsmA	FP2_30760	FP2_01630	Mg-dependent DNase.	Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.	0.597
FP2_30760	tsaD	FP2_30760	FP2_26330	Mg-dependent DNase.	O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.	0.548
guaA	FP2_25810	FP2_21030	FP2_25810	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Inactive homolog of metal-dependent proteases, putative molecular chaperone.	0.439
guaA	pheS	FP2_21030	FP2_18670	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	phenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.	0.569
guaA	pheT	FP2_21030	FP2_18680	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.	0.869
guaA	polA	FP2_21030	FP2_26340	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.738
guaA	rsmA	FP2_21030	FP2_01630	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.	0.567
guaA	tsaD	FP2_21030	FP2_26330	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.	0.515
pheS	guaA	FP2_18670	FP2_21030	phenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.	GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.	0.569

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