close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FP2_27090Anti-anti-sigma factor; Belongs to the anti-sigma-factor antagonist family. (108 aa)    
Predicted Functional Partners:
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
 
 0.999
FP2_27110
RNA polymerase sigma factor, sigma-70 family.
 
 
 0.944
FP2_01280
Diguanylate cyclase (GGDEF) domain.
  
  
 0.795
FP2_30670
Diguanylate cyclase (GGDEF) domain.
  
  
 0.795
FP2_08190
Stage IV sporulation protein B.
  
     0.769
FP2_01970
Stage II sporulation protein R (spore_II_R).
  
     0.768
FP2_07620
Uncharacterized protein conserved in bacteria.
  
     0.768
FP2_12240
Stage V sporulation protein AC.
  
     0.768
FP2_12220
SpoVA protein.
  
     0.767
FP2_12360
Transcriptional regulator, AbrB family.
  
     0.767
Your Current Organism:
Faecalibacterium prausnitzii L26
NCBI taxonomy Id: 718252
Other names: F. prausnitzii L2-6, Faecalibacterium prausnitzii L2-6, Faecalibacterium prausnitzii str. L2-6, Faecalibacterium prausnitzii strain L2-6, butyrate-producing bacterium L2-6
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.