STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FP2_27480RNA polymerase, sigma subunit, RpsG/SigG; Belongs to the sigma-70 factor family. (255 aa)    
Predicted Functional Partners:
FP2_08180
Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.853
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.853
FP2_11350
Stage II sporulation protein E (SpoIIE).
  
  
 0.847
FP2_01970
Stage II sporulation protein R (spore_II_R).
 
     0.815
FP2_27470
Stage III sporulation protein D.
  
  
 0.805
FP2_12360
Transcriptional regulator, AbrB family.
  
   
 0.793
FP2_05980
Sporulation protein YtfJ.
  
   
 0.777
FP2_12240
Stage V sporulation protein AC.
  
     0.773
FP2_07620
Uncharacterized protein conserved in bacteria.
  
   
 0.772
FP2_08190
Stage IV sporulation protein B.
  
     0.772
Your Current Organism:
Faecalibacterium prausnitzii L26
NCBI taxonomy Id: 718252
Other names: F. prausnitzii L2-6, Faecalibacterium prausnitzii L2-6, Faecalibacterium prausnitzii str. L2-6, Faecalibacterium prausnitzii strain L2-6, butyrate-producing bacterium L2-6
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.