| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FP2_15380 | FP2_15400 | FP2_15380 | FP2_15400 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases. | 0.996 |
| FP2_15380 | FP2_28050 | FP2_15380 | FP2_28050 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Phosphoribosylamine-glycine ligase. | 0.797 |
| FP2_15380 | FP2_32010 | FP2_15380 | FP2_32010 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Orotate phosphoribosyltransferase. | 0.786 |
| FP2_15380 | carA | FP2_15380 | FP2_15430 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | 0.995 |
| FP2_15380 | carB | FP2_15380 | FP2_15440 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Carbamoyl-phosphate synthase large subunit. | 0.995 |
| FP2_15380 | pyrB | FP2_15380 | FP2_05360 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
| FP2_15380 | pyrD | FP2_15380 | FP2_15410 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Dihydroorotate oxidase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. | 0.998 |
| FP2_15380 | pyrE | FP2_15380 | FP2_15420 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Orotate phosphoribosyltransferase, Thermus family; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.947 |
| FP2_15380 | pyrF | FP2_15380 | FP2_15390 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | Orotidine 5'-phosphate decarboxylase, subfamily 2; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.968 |
| FP2_15400 | FP2_15380 | FP2_15400 | FP2_15380 | 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.996 |
| FP2_15400 | FP2_28050 | FP2_15400 | FP2_28050 | 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases. | Phosphoribosylamine-glycine ligase. | 0.741 |
| FP2_15400 | FP2_32010 | FP2_15400 | FP2_32010 | 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases. | Orotate phosphoribosyltransferase. | 0.972 |
| FP2_15400 | carA | FP2_15400 | FP2_15430 | 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases. | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. | 0.945 |
| FP2_15400 | carB | FP2_15400 | FP2_15440 | 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases. | Carbamoyl-phosphate synthase large subunit. | 0.942 |
| FP2_15400 | pyrB | FP2_15400 | FP2_05360 | 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases. | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.913 |
| FP2_15400 | pyrD | FP2_15400 | FP2_15410 | 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases. | Dihydroorotate oxidase B, catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. | 0.999 |
| FP2_15400 | pyrE | FP2_15400 | FP2_15420 | 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases. | Orotate phosphoribosyltransferase, Thermus family; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.994 |
| FP2_15400 | pyrF | FP2_15400 | FP2_15390 | 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases. | Orotidine 5'-phosphate decarboxylase, subfamily 2; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.953 |
| FP2_28050 | FP2_15380 | FP2_28050 | FP2_15380 | Phosphoribosylamine-glycine ligase. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.797 |
| FP2_28050 | FP2_15400 | FP2_28050 | FP2_15400 | Phosphoribosylamine-glycine ligase. | 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases. | 0.741 |