Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPRED3Sprouty-related, EVH1 domain-containing protein 3. (443 aa)    
Predicted Functional Partners:
NF1
Neurofibromin.
    
 0.695
SPRED1
Sprouty-related, EVH1 domain-containing protein 1.
     
 0.639
NUDT6
Nucleoside diphosphate-linked moiety X motif 6; Belongs to the Nudix hydrolase family.
      
 0.545
C19orf54
Uncharacterized protein.
      
 0.542
STAM
Signal transducing adapter molecule 1.
      
 0.539
ABL1
Tyrosine-protein kinase.
    
 0.529
ABL2
ABL proto-oncogene 2, non-receptor tyrosine kinase.
    
 0.529
KCTD14
BTB/POZ domain-containing protein KCTD14.
      
 0.528
SPHKAP
A-kinase anchor protein SPHKAP.
      
 0.493
TSNAXIP1
Translin-associated factor X-interacting protein 1.
      
 0.490
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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