STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FGF12Fibroblast growth factor 11/12/13. (243 aa)    
Predicted Functional Partners:
FGFR1
Basic fibroblast growth factor receptor 1.
    
 0.808
IGF1
Insulin-like growth factor I.
      
 0.701
FGFR3
Fibroblast growth factor receptor 3.
    
 0.688
FGFR2
Fibroblast growth factor receptor.
    
 0.669
SCN5A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
    
 
 0.639
INS
Insulin.
   
  
 0.631
FGFR4
Fibroblast growth factor receptor.
    
 0.630
CDH2
Cadherin-2; Cadherins are calcium-dependent cell adhesion proteins.
   
  
 0.630
FGF8
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
      
 0.626
ALB
Serum albumin.
      
 0.625
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.