Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ASCL3Achaete-scute-like protein 3. (181 aa)    
Predicted Functional Partners:
TCF3
Transcription factor E2-alpha.
   
 0.844
TCF4
Transcription factor 4.
   
 0.737
TCF12
Transcription factor 4/12.
   
 0.727
TRPM5
Transient receptor putative cation channel subfamily M member 5.
      
 0.683
ACSL3
Long-chain-fatty-acid--CoA ligase 3.
    
 
 0.661
ID1
DNA-binding protein inhibitor ID-1.
    
 0.647
CCDC153
Coiled-coil domain containing 153.
      
 0.618
FOXI1
Forkhead box protein I1.
    
 0.616
BSCL2
Seipin.
      
 0.615
CFTR
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
   
  
 0.597
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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