STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K4Mitogen-activated protein kinase kinase kinase 4. (1559 aa)    
Predicted Functional Partners:
GADD45B
Growth arrest and DNA damage-inducible protein GADD45 beta.
    
 0.964
GADD45A
Growth arrest and DNA damage-inducible protein GADD45 alpha.
    
 0.954
MAP2K3
Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.
    
0.952
GADD45G
Growth arrest and DNA damage-inducible protein GADD45 gamma.
    
 0.951
MAP2K6
Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.
    
0.945
MAP2K5
Dual specificity mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.
   
 
0.694
MAP2K1
Mitogen-activated protein kinase kinase 1.
   
 
0.684
MAP2K2
Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily.
   
 
0.684
PDK1
Protein-serine/threonine kinase.
   
 
 0.542
PDK4
Protein-serine/threonine kinase.
   
 
 0.542
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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