STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACSL1Acyl-CoA synthetase long-chain family member 1. (698 aa)    
Predicted Functional Partners:
FASN
Fatty acid synthase, animal type.
   
 0.961
CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform; Belongs to the carnitine/choline acetyltransferase family.
   
 
 0.910
LPL
Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
     
 0.849
PPT1-2
Palmitoyl-protein thioesterase 1.
   
 
 0.828
PPT2
Lysosomal thioesterase PPT2.
   
 
 0.824
ACSL3
Long-chain-fatty-acid--CoA ligase 3.
  
0.810
CPT1B
Carnitine O-palmitoyltransferase 1, muscle isoform; Belongs to the carnitine/choline acetyltransferase family.
   
 
 0.808
ACSL4
Long-chain-fatty-acid--CoA ligase 4.
  
0.778
PNPLA2
Patatin-like phospholipase domain-containing protein 2.
   
 
 0.774
ACACA
Acetyl-CoA carboxylase / biotin carboxylase 1.
   
  
 0.732
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.