STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAGEE2Melanoma-associated antigen E2. (523 aa)    
Predicted Functional Partners:
NSMCE4A
Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
   
 0.759
SMC6
Structural maintenance of chromosomes protein 6.
   
 0.734
NSMCE2
E3 SUMO-protein ligase NSE2.
    
 0.717
SMC5
Structural maintenance of chromosomes protein 5.
   
 0.702
FAM229B
Uncharacterized protein.
      
 0.679
NSMCE1
Non-structural maintenance of chromosomes element 1-like protein.
   
 0.664
ENSBMUP00000018913
annotation not available
   
 0.664
CLIC2
Chloride intracellular channel protein 2.
      
 0.530
ZSWIM7
Zinc finger SWIM domain-containing protein 7.
      
 0.526
GNG12
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
  
 0.525
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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