STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DSC1Desmocollin-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (893 aa)    
Predicted Functional Partners:
JUP
Junction plakoglobin.
   
 0.892
DSG1
Desmoglein-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
   
0.849
CDSN
Corneodesmosin.
   
 
 0.794
DSP
Desmoplakin.
   
 0.784
PKP2
Plakophilin-2.
   
 0.760
DSG2
Desmoglein-2.
   
0.757
PLEC
Poly [ADP-ribose] polymerase.
   
 0.749
PKP3
Plakophilin 3.
   
 0.731
PKP1
Plakophilin-1.
   
 0.703
DSG3
Desmoglein 3.
   
0.629
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.