STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPINK1Pancreatic secretory trypsin inhibitor. (79 aa)    
Predicted Functional Partners:
LOC102269813
Cationic trypsin; Belongs to the peptidase S1 family.
   
 0.905
LOC102282347
Cationic trypsin.
   
 0.905
PRSS2
Protease, serine 2.
   
 0.889
CTRC
Chymotrypsin-C; Belongs to the peptidase S1 family.
   
 0.697
LOC102265599
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 0.631
LOC102287233
Chymotrypsinogen B; Belongs to the peptidase S1 family.
   
 0.631
SPINK9
Serine protease inhibitor Kazal-type 9.
      
 0.612
WFDC3
WAP four-disulfide core domain protein 3.
      
 0.606
TMPRSS15
Enteropeptidase; Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.
    
 0.534
LOC102267066
Proproteinase E; Belongs to the peptidase S1 family.
   
 0.523
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.