STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F5Coagulation factor V; Belongs to the multicopper oxidase family. (2177 aa)    
Predicted Functional Partners:
F2
Prothrombin; Belongs to the peptidase S1 family.
    
  0.907
PROS1
Vitamin K-dependent protein S.
     
  0.900
MYSM1
Histone H2A deubiquitinase MYSM1.
   
 0.727
ITSN2
Intersectin-2.
     
 0.676
DCTN2
Dynactin subunit 2.
   
 0.554
CAPZB
Capping protein (actin filament) muscle Z-line, beta.
   
 0.547
ACTR8
Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.
    
 0.530
WDR1
WD repeat-containing protein 1.
   
 0.527
DCTN6
Dynactin subunit 6.
    
 0.525
SMARCB1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family.
   
 0.525
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.