STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGO1Protein argonaute-1; Belongs to the argonaute family. (1020 aa)    
Predicted Functional Partners:
DICER1
Endoribonuclease Dicer; Belongs to the helicase family. Dicer subfamily.
   
 0.943
AGO2
Protein argonaute-2.
  
 
0.932
AGO4
Eukaryotic translation initiation factor 2C.
  
  
0.908
DROSHA
Ribonuclease 3.
   
 0.852
TARBP2
RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...]
    
 0.811
PRKRA
Interferon-inducible double stranded RNA-dependent protein kinase activator A.
    
 0.765
STAU2
Double-stranded RNA-binding protein Staufen-like protein 2.
    
 0.731
MRPL44
39S ribosomal protein L44, mitochondrial.
   
 0.686
STAU1
Double-stranded RNA-binding protein Staufen-like protein 1.
    
 0.648
TSN
Translin.
   
 0.631
Your Current Organism:
Bos mutus
NCBI taxonomy Id: 72004
Other names: B. mutus, Bos grunniens mutus, Poephagus mutus, wild yak
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